Pseudoephedrine (Sudafed)
NHS information about pseudoephedrine, including what it's used for, who can take it, how to take it and side effects.
What pseudoephedrine is for
Pseudoephedrine is used to treat a blocked nose caused by:
- the common cold
- flu
- allergies such as hay fever
- a sinus infection (sinusitis)
It works by reducing swelling to help mucus and air move through more easily.
Sometimes pseudoephedrine comes mixed with other medicines, such as painkillers or antihistamines. This information is about pseudoephedrine on its own.
How to take pseudoephedrine and how much to take
Pseudoephedrine comes as tablets or a liquid that you swallow.
It's usually only used for a short time at the lowest dose, until your symptoms have improved.
Always check the packet or leaflet that comes with your medicine. Ask a pharmacist or doctor for advice if you're not sure how to take it or have any problems taking it.
How to take common types of pseudoephedrine
Side effects of pseudoephedrine
Like all medicines, pseudoephedrine can cause side effects, although not everyone gets them.
Common side effects
Common side effects of pseudoephedrine include:
- feeling sick (nausea)
- headaches
- a dry mouth
- feeling nervous
- difficulty sleeping
Who can and cannot take pseudoephedrine
Most adults and children aged 6 years and over can take pseudoephedrine.
Taking pseudoephedrine with other medicines, food and drink
There are some medicines, remedies and supplements that may not mix well with pseudoephedrine.
This includes some types of:
- antidepressants, such as tricyclic antidepressants or monoamine oxidase inhibitors (MAOIs)
- medicines for heart failure, such as digoxin
- medicines for high blood pressure, such as beta blockers or methyldopa
- other cough and cold medicines – do not take pseudoephedrine with other medicines for a blocked nose, such as xylometazoline and oxymetazoline as it could make symptoms worse
This is not the full list of medicines that may not mix well with pseudoephedrine. Tell your doctor or pharmacist if you're taking any other medicines, herbal remedies, vitamins or supplements.
Food, drink and alcohol with pseudoephedrine
You can eat and drink normally (including alcohol) while taking pseudoephedrine.
